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(Posted March 14, 2010) "During the past 3 decades, total calorie intake has increased by an average of 150 to 300 calories per day, approximately half of which comes from sugar-sweetened beverages. Potential harms of excessive sugar intake may include excessive weight gain, metabolic abnormalities, adverse health conditions, and essential nutrient deficiencies. A prudent upper limit of added sugar intake is half of the discretionary calorie allowance (≤ 100 calories per day for most US women and ≤ 150 calories per day for most US men)."; "...when people choose lower-calorie dishes, they just compensate by eating bigger portions."; "...simple carbohydrates (like crackers, bread, or cookies) elicit a quick rise in blood sugar and insulin levels, which subsequently drop just as quickly, causing dramatic shifts in both mood and appetite."; "Patients who consume a diet rich in high-fat dairy products and fried, refined, and sugary foods are at increased risk of developing depression, whereas those whose diet is rich in fish, fruit, and vegetables are at lower risk of developing depression,.."; "...refined carbohydrates and foods with high sugar and fat content promote what he calls "fullness resistance." They interfere with the complex hormonal messages the body usually sends to the brain to signal that it's time to stop eating. People feel hungrier instead...because refined carbohydrates raise blood-sugar levels, setting up an insulin surge that drives blood sugar down again, causing rebound hunger. That insulin spike also interferes with leptin, the hormone secreted by fat cells that should tell the body to stop eating. The body also becomes resistant to insulin, setting the stage for diabetes."; "Postmenopausal women who eat the most fat have an elevated risk of ischemic stroke....Those who ate the most total fat -- a median of 95 grams/day -- were 44% more likely to have an ischemic stroke than those who ate the least -- a median of 25 grams/day ... Women who ate the most trans fat -- a median of 7.5 grams/day -- also had an elevated stroke risk compared with those who ate the least -- a median of 1.3 grams/day...."; "The regular consumption of sugar-laden soft drinks could boost a person's risk of developing pancreatic cancer....individuals who consumed 2 or more soft drinks per week had an 87% increased risk for pancreatic cancer, compared with those who did not. The high levels of sugar can increase levels of insulin in the body, and this can contribute to pancreatic cancer cell growth...."; "Limiting intake of carbohydrates, particularly refined carbohydrates, offers the best hope for reducing the CVD burden associated with atherogenic dyslipidemia."Replacement of saturated fat by polyunsaturated or monounsaturated fat lowers both LDL and HDL cholesterol,... However, replacement with a higher carbohydrate intake, particularly refined carbohydrate, can exacerbate the atherogenic dyslipidemia associated with insulin resistance and obesity that includes increased triglycerides, small LDL particles, and reduced HDL cholesterol."; "Eating fast may curtail the release of hormones that help regulate appetite, potentially leading to overeating."; "...dieters who stuck to low fat consumption had lasting reductions in hostility, confusion, depression, and overall bad mood scores during one year of dieting compared with those on a low-carb diet."; "Diet soda may help keep your calories in check, but drinking two or more diet sodas a day may double your risk of declining kidney function. Women who drank two or more diet sodas a day had a 30% drop in a measure of kidney function during the lengthy study follow-up."; "Reduced-calorie diets result in clinically meaningful weight loss regardless of which macronutrients they emphasize."

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